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Gender Influence on Hospital Mortality after Coronary Artery Bypass Surgery

Tehran Heart Center, Tehran University of Medical Sciences Tehran, Iran

For reprint information contact: Amir H Lebaschi, MD Tel: 98 91 2315 9507 Fax: 98 21 6693 7185 Email: ah_lebaschi{at}razi.tums.ac.ir, Head Office of the Department of Surgery, Imam Medical Complex, Tehran University of Medical Sciences, Tehran, Iran.

There is still controversy about the influence of gender on hospital mortality after coronary artery bypass grafting. We analyzed various risk factors in 1,258 patients undergoing isolated on-pump coronary artery bypass, of whom 19 (1.5%) died in hospital. There were 937 men (74.5%) and 321 women (25.5%). Compared to men, women were older with a higher mean body mass index, twice as many were hypertensive and diabetic, and they had higher serum cholesterol and triglycerides. Men smoked more, had lower ejection fractions, more myocardial infarctions and poorer functional status. Female sex, congestive heart failure, low ejection fraction, diabetes, previous percutaneous interventions and chronic lung disease were more prevalent among the patients who died. These factors were used to form a logistic regression model in which sex did not have an independent influence on hospital mortality. The difference between men and women can be explained by differences in risk factor profile.