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Asian Cardiovasc Thorac Ann 2006;14:10-13
© 2006 Asia Publishing EXchange Ltd

ORIGINAL CONTRIBUTION

Low-Prime System Minimizes Transfusions and Hemodilution in Coronary Bypass

Sven Beholz, MD, Liling Zheng, MD, Martin Rusche, EBCP, Michael Kessler, EBCP, Wolfgang Konertz, PhD

Department of Cardiovascular Surgery, Charité-University, Berlin Berlin, Germany

For reprint information contact: Sven Beholz, MD, Tel: 49 30 450 522 196, Fax: 49 30 450 522 921, Email: sven.beholz{at}charite.de, Department of Cardiovascular Surgery, Charité-University Medicine Berlin, Schumannstr. 20/21, Berlin 10117, Germany.

Standard heart-lung machines lead to substantial hemodilution with associated impaired organ function and increased need for blood transfusions. The aim of this study was to evaluate the effect of the new PRECiSe low prime volume system on perioperative myocardial damage, hemodilution, and transfusions. In a case-matched prospective study, 40 patients undergoing coronary artery bypass surgery using PRECiSe were compared with 40 patients on a standard heart-lung machine. In the PRECiSe group, the prime volume was significantly reduced, resulting in less hemodilution and transfusion requirements during and after extracorporeal circulation: only 10% of patients needed transfusions vs. 35% in the control group, with an average transfusion need of 0.16 vs. 1.25 units. There were no significant differences in perioperative cardiac-specific enzymes. The PRECiSe system was considered safe and effective for coronary artery bypass surgery.






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